Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days

Launched by HACKENSACK MERIDIAN HEALTH · Apr 18, 2023

Keywords

ClinConnect Summary

This clinical trial is studying whether taking two medications, ondansetron and ibuprofen, before a medical abortion can help reduce side effects like nausea and pain. The goal is to see if this approach can make the experience more comfortable for patients and increase their satisfaction with the procedure.

To participate, you need to be a healthy woman aged between 18 and 62 who is planning to have a medical abortion and can confirm your pregnancy is less than 70 days through an ultrasound. You should also be able to speak English and have a way to keep track of time for follow-ups. It's important to note that if you have certain health conditions or allergies, or if you are taking specific medications, you may not be eligible. If you join the trial, you can expect to receive the medications and have follow-up calls or visits to discuss your experience.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Healthy
• • English speaking
• • female volunteers undergoing medical abortion whether for voluntary interruption of pregnancy or missed abortion
• • Gestational age \</= 70 days confirmed via ultrasound
• • Access to a time keeping device
• • Willingness to complete a telephone or in-clinic follow up
• Exclusion Criteria:
• • chronic medical problems including but not limited to cardiac conditions, malignancy or organ damage
• • Failed medical abortion resulting in surgical management
• • Known intrauterine infection
• • Known allergy to ondansetron or ibuprofen
• • Subjects chronically receiving analgesic drugs
• • Subjects unable to give consent
• • Subjects taking medications that interact with ondansetron or ibuprofen