The Clinical Course and Factors for the Progression of Uninvestigated Dyspepsia to Functional Dyspepsia

Launched by AIR FORCE MILITARY MEDICAL UNIVERSITY, CHINA · Apr 10, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a condition called dyspepsia, which is a common digestive issue that causes symptoms like stomach pain, feeling full after eating, or burning sensations in the stomach. The focus of the trial is to understand how dyspepsia can progress to a more serious form called functional dyspepsia, which is diagnosed when symptoms last for six months or more. Researchers want to learn more about the natural course of this condition and what factors might influence its progression.

To participate in the trial, individuals must be at least 18 years old and have experienced their first symptoms of dyspepsia for more than one month but less than three months. However, people with certain medical conditions, such as ulcers, liver or kidney diseases, or other serious health issues, are not eligible to join. Participants in the trial will be monitored to help researchers gather important information about dyspepsia and how it may develop over time. This research could lead to better understanding and treatments for those suffering from this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged ≥ 18 years old who had first-onset dyspepsia with one or more symptoms of epigastric pain, epigastric burning, postprandial fullness, early satiation and that has lasted for more than 1 month to 3 months.
• Exclusion Criteria:
• 1. Patients with local or systemic diseases which may cause dyspeptic symptoms:
• • Known active peptic ulcer, cholecystitis, gallstone, gastrointestinal obstruction, gastroparesis, and etc.
• • 2. Known acute or chronic injury of liver or kidney
• • 3. Obvious hematological abnormality, or endocrine and metabolic diseases
• • 4. Known malignancy; Obvious cardiovascular or cerebrovascular diseases (such as coronary heart disease, arrhythmia, cerebral infarction and etc.
• • 5. Other conditions which may be associated with dyspeptic symptoms (such as NSAIDs associated dyspepsia)
• • 6. organ failure defined by Marshall standard or severe psychiatric illnesses
• • 7. pregnancy or lactation
• • 8. unable to provide consent