Prone Positioning and Abdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing

Launched by UNIVERSITY OF CHILE · Apr 21, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different positioning and support methods can help protect the lungs and muscles of patients with Acute Respiratory Distress Syndrome (ARDS) who are transitioning from mechanical ventilation to spontaneous breathing. Specifically, the researchers want to see if lying face down (prone positioning) or using a special binding around the abdomen while lying on the back can reduce injuries to the lungs and muscles that often occur during this transition. This is important because complications from long-term mechanical ventilation can make it harder for patients to recover and can lead to more serious health issues.

To be eligible for the study, participants must be adults with moderate to severe ARDS who have been on a mechanical ventilator for more than three days and have stable vital signs. They should also be alert enough to start breathing on their own. Participants in the trial will undergo assessments to understand their muscle and lung function better and will be placed in different positions to see which method helps them breathe more easily and safely. This study aims to find better ways to support patients during a critical time in their recovery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult ARDS patients with moderate-severe ARDS on controlled protective mechanical ventilation for more than 3 days
• • Stable hemodynamics
• • Level of consciousness enough to initiate spontaneous breathing
• Exclusion Criteria:
• • Unstable hemodynamics
• • Tracheostomy
• • Abnormal level of consciousness
• • Central nervous system injury
• • Esophageal varices
• • Pregnancy
• • Contraindications for installation of electrical impedance tomography or ultrasound assessments