Ultrasound Changes of the Vagus Nerve in Patients With Parkinsonism

Launched by ASSIUT UNIVERSITY · Apr 27, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at changes in the Vagus nerve in people with parkinsonism, a condition that affects movement and can cause other symptoms. The researchers will compare two groups: one group of patients diagnosed with parkinsonism and another group of healthy individuals who are similar in age and gender. The goal is to see how the Vagus nerve differs between these groups and how these differences relate to the symptoms experienced by those with parkinsonism.

To participate in this study, individuals must have a diagnosis of parkinsonism and be willing to undergo various examinations. Both men and women are eligible, but those who cannot give their consent or have certain other health issues, like severe psychiatric problems or previous surgeries near the Vagus nerve, will not be included. Participants can expect to have their Vagus nerve assessed using ultrasound, which is a painless procedure, and their results will help researchers better understand the condition. This study is currently recruiting participants.

Gender

ALL

Eligibility criteria

• A) Inclusion Criteria:
• • All patients fulfill the criteria of case definition of parkinsonism.
• • Gender: both sexes are included.
• • Willingness to participate in the study and to be subjected to the disease-related examinations and assessments.
• • Willing and able to provide informed consent.
• B) Exclusion Criteria:
• • Patients unable to give informed consent.
• • History of chronic psychiatric or other central nervous system pathology and other neurodegenerative disorder(s).
• • Patients with previous surgery in proximity of the Vagus nerve (for example carotid endarterectomy or implantation of Vagus nerve stimulator).
• • Patients with known systemic diseases (such as diabetes mellitus, vascular disease, and peripheral neuropathy).