Magnetoencephalography by Optical Pumping Magnetometer

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Apr 26, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to measure brain activity using a technique called Magnetoencephalography (MEG). This method is better than older techniques because it can capture brain activity more accurately and quickly. The researchers want to see if a new type of sensor, called Optical Pumping Magnetometers (OPM), can be used instead of the traditional sensors, which are expensive and complicated. The goal is to identify markers that show how a healthy brain develops in both adults and newborns, including those born prematurely.

To participate in the trial, healthy adults aged 18 to 65, as well as newborns born at term (38-42 weeks) or prematurely (28-36 weeks), may be eligible, as long as they do not have any medical conditions or are receiving treatment. Pregnant women between 28 and 40 weeks along can also take part, provided they are healthy. Participants can expect to undergo brain activity measurements while lying still for a short time, and it's important to note that some individuals, like those with certain medical devices or conditions, may not be able to participate. This study could help improve our understanding of brain development in both adults and infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • For healthy adult volunteers
• • Age between 18 and 65
• • No pathology, no treatment
• • No toxicant intake
• • For term newborns
• • Child between 38 and 42 weeks gestational age on the day of registration
• • No pathology, no treatment
• • For children born prematurely
• • Child between 28 and 36 weeks gestational age on the day of registration
• • No pathology, no treatment apart from routine care related to prematurity
• • For pregnant women
• • Pregnant with between 28 to 40 weeks gestational age on the day of registration
• • No pathology, no treatment
• Exclusion Criteria:
• • Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible.
• • Patients who cannot stand to stand still for a few minutes.
• • Newborn on ventilatory assistance or infusion
• • Newborn baby not meeting the age criteria