A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors

Launched by UNIVERSITY OF CALIFORNIA, IRVINE · Apr 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new therapy called Goal-focused Emotion-Regulation Therapy (GET) to help young adult men who have survived testicular cancer. The goal of the trial is to see if this therapy can reduce feelings of distress, anxiety, and depression while also improving skills for managing emotions and setting goals. Participants, aged 18 to 39, who have completed chemotherapy for testicular cancer in the past four years and are experiencing significant distress will be invited to take part.

During the study, participants will be randomly assigned to receive either six sessions of GET or a supportive listening program over eight weeks. Researchers will measure various outcomes, like changes in mood and ability to cope with stress, at different points: before the sessions, right after, and then again at 12 and 24 weeks later. The trial is currently recruiting participants, and it's important to note that those with certain psychiatric or medical conditions, or who smoke regularly, may not be eligible. Overall, this study seeks to provide valuable support and resources to help young cancer survivors navigate their emotions and goals more effectively.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Age 18 to 39 years at time of consent
• • A confirmed diagnosis of testis cancer (any stage)
• • Completion of chemotherapy for testis cancer within 4 years prior to consent
• • A score of \>4 on the Distress Thermometer
• • English fluency, as per medical record documenting preferred language or in the judgment of the investigator
• • Spanish fluency, as per medical record documenting preferred language or in the judgment of the investigator
• • Able to perform informed consent
• Exclusion Criteria:
• • Lifetime history of psychiatric of cognitive disturbance as per self-report or medical record
• • In the judgment of the consenting professional, is unable to provide informed consent and complete study sessions and assessment
• • As per self-report, has medical conditions that affect the immune system and would confound immune evaluation (e.g., autoimmune disorder, inflammatory disease; uncontrolled thyroid disease; active infection; myocardial infarction or stroke in the last 6 months; Type I diabetes; acute hepatitis; recent vaccination for viral disease)
• • Regular smoker (daily use)