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Search / Trial NCT05837221

Microbiome in Head and Neck Squamous Cell Carcinoma

Launched by UNIVERSITY OF COLORADO, DENVER · Apr 19, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying the role of the microbiome, which is the collection of bacteria and other microorganisms in our bodies, in a type of cancer called head and neck squamous cell carcinoma (HNSCC). Researchers want to find out if changes in these microorganisms contribute to the development of this cancer and understand how this happens at a molecular level.

To participate in the study, you need to be at least 18 years old and have been diagnosed with oral squamous cell carcinoma (OSCC). The researchers are also looking for a similar number of participants who do not have this diagnosis to serve as a comparison group. If you join the study, you can expect to have your health evaluated by a doctor at the University of Colorado Health and will need to sign a consent form agreeing to participate. This research could help improve our understanding of head and neck cancers and potentially lead to better treatments in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Subjects equal to or above the age of 18.
  • 2. Patients who are seen and evaluated by a provider within the adult Otolaryngology clinic at the University of Colorado Health.
  • 3. Patients that present with a diagnosis of OSCC.
  • 4. An equal number of age-matched patients who are visiting the clinic for reasons other than OSCC diagnoses, as the control group.
  • 5. Ability to understand and willingness to sign a written informed consent document
  • Exclusion Criteria:
  • 1. Subjects under the age of 18 or over the age of 100
  • 2. Subjects unwilling to particiapte

About University Of Colorado, Denver

The University of Colorado, Denver, is a leading academic institution dedicated to advancing medical research and improving healthcare outcomes. With a strong emphasis on innovation and collaboration, the university conducts a diverse range of clinical trials aimed at addressing critical health challenges. Its research initiatives are supported by a multidisciplinary team of experts, state-of-the-art facilities, and a commitment to ethical standards and patient safety. By fostering partnerships with local and global communities, the University of Colorado, Denver, strives to translate scientific discoveries into meaningful advancements in clinical practice and public health.

Locations

Aurora, Colorado, United States

Patients applied

0 patients applied

Trial Officials

Shi-Long E Lu, MD, PhD

Principal Investigator

University of Colorado, Denver

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported