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Search / Trial NCT05837663

Trifecta-Lung cfDNA-MMDx Study

Launched by UNIVERSITY OF ALBERTA · Apr 18, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Donor Derived Cf Dna Gene Expression Lung Transplant Biopsy Blood

ClinConnect Summary

The Trifecta-Lung cfDNA-MMDx Study is a clinical trial aimed at understanding how certain levels of genetic material (called dd-cfDNA) in the blood relate to specific antibodies in lung transplant recipients. The study will also evaluate a testing system called the Molecular Microscope® (MMDx), which helps doctors assess the health of lung transplants through special biopsies. This research is important because it could improve the way doctors monitor lung transplant patients and help ensure their long-term success.

To participate in this study, you must be an adult aged 65 to 74 who has received a lung transplant. Unfortunately, individuals who are unable to give informed consent, those who have received multiple organ transplants, cancer patients, and pregnant women cannot take part in this trial. If you join, you can expect to undergo blood tests and biopsies as part of the study, which will help researchers gather valuable information about lung health after transplantation. Your participation could contribute to advancing care for future lung transplant patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult, Older adult
  • Exclusion Criteria:
  • Patients will be excluded from the study if they decline participation Are unable to give informed consent. Recipients of multiple organs, cancer patients and pregnant women

About University Of Alberta

The University of Alberta, a leading research institution in Canada, is dedicated to advancing healthcare through innovative clinical trials. With a strong commitment to scientific excellence and community health, the university facilitates cutting-edge research across various medical disciplines. Its interdisciplinary approach fosters collaboration among researchers, clinicians, and students, ensuring that clinical trials are designed and conducted with the utmost rigor and ethical standards. By leveraging its extensive resources and expertise, the University of Alberta aims to translate research findings into meaningful advancements in patient care and public health.

Locations

Toronto, Ontario, Canada

Melbourne, , Australia

Vienna, , Austria

Edmonton, Alberta, Canada

Prague, , Czechia

Edmonton, Alberta, Canada

Prague, , Czechia

Dallas, Texas, United States

Gainesville, Florida, United States

New York, New York, United States

Tampa, Florida, United States

Patients applied

0 patients applied

Trial Officials

Philip F Halloran, MD PhD

Principal Investigator

Alberta Transplant Applied Genomics Centre, University of Alberta

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported