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Search / Trial NCT05838365

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

Launched by UNIVERSITY OF MILAN · Apr 26, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is investigating how well dental implants made of zirconia work when they are loaded immediately (within 7 days after placement) compared to those that are loaded later (8 weeks after placement). The study aims to see which method leads to better success rates for the implants after five years. Researchers will also look at other factors, such as the health of the surrounding bone and soft tissue, any complications that might arise, and how patients feel about their treatment through questionnaires.

To participate in this study, you need to be a healthy adult aged between 29 and 74 years who has lost some teeth in the back of your mouth (premolar or molar positions). You should have enough bone in your jaw to support the implant and be able to understand and agree to the treatment plan. However, individuals with serious health issues, heavy smoking habits, or certain other medical conditions may not be eligible. If you join the trial, you will receive careful monitoring and follow-up to ensure your implant is functioning well and to address any questions or concerns you may have throughout the process.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Sistemically healthy patients
  • partial edentulism
  • premolar position
  • molar position
  • Bone width and height at least 6 and 10mm, respectively.
  • Keratinized tissue, at least 1 mm at implant site
  • Full understanding of the proposed surgical treatments and the protocol schedule
  • Full comprehension and availability to sign the informed consent form
  • Exclusion Criteria:
  • Heavy smokers (\>10 cigarettes a day)
  • Serious kidney or liver diseases
  • Uncontrolled diabetes
  • Bisphosphonates intake
  • History of radiotherapy of the head and neck
  • Current antiblastic chemotherapy
  • Congenital (primary) or acquired (secondary) immunodeficiency
  • Pregnant women
  • Connective tissue disorders
  • Local exclusion criteria:
  • untreated stage III/IV periodontitis
  • Autoimmune diseases
  • oral parafunctions

About University Of Milan

The University of Milan is a prestigious academic institution renowned for its commitment to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university actively sponsors clinical trials aimed at enhancing healthcare outcomes and fostering innovation in medical science. Its research initiatives are guided by a dedication to ethical standards and rigorous scientific methodologies, ensuring that trials not only contribute to the body of knowledge but also prioritize patient safety and well-being. Through its extensive network of researchers and clinicians, the University of Milan plays a pivotal role in translating scientific discoveries into practical applications that benefit communities both locally and globally.

Locations

Milano, , Italy

Patients applied

DP

AG

2 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported