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Search / Trial NCT05838508

Effect of Physical Activity Pattern on Cardiometabolic Health

Launched by BRIGHAM AND WOMEN'S HOSPITAL · Apr 28, 2023

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Exercise Circadian System Physical Activity Glucose Tolerance Blood Pressure

ClinConnect Summary

This clinical trial is studying how our daily activities and exercise patterns affect our overall health, particularly in relation to heart and metabolic conditions. The researchers want to learn more about how our body's internal clock interacts with physical activity.

To participate in this study, you need to be between 18 and 45 years old, have a body mass index (BMI) between 25 and 34.9, and be in good health without serious medical conditions. Participants will spend time in a hospital, where they will exercise moderately, eat the same meals, and provide samples of blood, urine, and saliva for testing. If you qualify and choose to take part, you'll be closely monitored to help researchers understand the best ways to improve health through physical activity. Please note, individuals who smoke, are pregnant, or have certain health issues cannot participate.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18-45 yr old
  • Body mass index (BMI) 18.5 - 34.9 kg/m2
  • No acute, chronic or debilitating medical conditions (e.g. metabolic, cardiovascular, respiratory, neurological, cancers, etc.)
  • Willing to adhere to the protocol requirements for the duration of the study
  • Exclusion Criteria:
  • Currently smoking/vaping or 5 or more years of smoking/vaping
  • Currently pregnant or breastfeeding
  • History of drug or alcohol dependency
  • History of psychiatric illness or disorder
  • Any hospitalization due to COVID-19
  • Inability to exercise for any reason
  • Any known contraindication to exercise testing based on current ACSM guidelines

About Brigham And Women's Hospital

Brigham and Women's Hospital (BWH) is a leading academic medical center located in Boston, Massachusetts, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As an integral part of the Partners HealthCare system, BWH combines cutting-edge medical education with a focus on patient-centered care, fostering an environment that promotes groundbreaking clinical trials across various specialties. The hospital is dedicated to translating scientific discoveries into effective treatments, making significant contributions to the fields of cardiovascular medicine, oncology, and women's health, among others. With a robust infrastructure for research and a collaborative approach, BWH aims to improve patient outcomes and enhance the overall quality of healthcare.

Locations

Boston, Massachusetts, United States

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Jingyi Qian, PhD

Principal Investigator

Brigham and Women's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported