The Usefulness of Myocardial Work IndeX in ExtraCorporeal Membrane Oxygenation Patients

Launched by SEMMELWEIS UNIVERSITY HEART AND VASCULAR CENTER · Apr 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new way to assess heart function in patients who are receiving a treatment called veno-arterial extracorporeal membrane oxygenation (VA-ECMO). VA-ECMO is a life-support system used for patients in severe heart failure or cardiogenic shock, helping to provide oxygen to the body when the heart cannot do so effectively. The researchers want to see if a method called myocardial work index, which is a non-invasive way to measure how well the heart is working, can help predict outcomes for these patients.

To be eligible for this trial, participants must be 18 years or older and experiencing severe heart failure that requires VA-ECMO. They should be stable in terms of blood flow and oxygen levels while receiving this treatment. However, patients with unstable conditions, severe brain damage, or certain other health issues will not be included. Participants will need to provide consent, and due to the trial's nature, a legally eligible relative may need to sign on their behalf. While the trial is not yet recruiting, it aims to gather valuable information about heart function in critically ill patients to improve their care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years or older age
• • Severe cardiogenic shock requiring the initiation of VA-ECMO therapy
• • Stabile hemodynamic state and oxigenation with VA-ECMO and vasoactive support
• • Informed written consent (due to the nature of the study, from a legally eligible relative of the patient)
• Exclusion Criteria:
• • Younger than 18 years of age
• • Unstable hemodynamic state or suboptimal oxigenation despite established VA-ECMO and vasoactive support
• • Severe neurological damage or confirmed brain death at the time of enrollment which squarely indicates therapy limitation and poor short-term outcome
• • Transesophageal echocardiography is contraindicated
• • Suboptimal echocardiographic window