Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

Launched by UNIVERSITY OF MIAMI · Apr 19, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring whether a Mediterranean diet and exercise program can help lymphoma patients during their chemotherapy treatment. The researchers want to see if these lifestyle changes can make it easier for patients to complete their treatment and lessen any side effects they might experience. If you're an adult aged 18 or older, diagnosed with untreated Non-Hodgkin or Hodgkin lymphoma, and scheduled for at least six cycles of chemotherapy, you might be eligible to participate.

Participants will be randomly assigned to either follow the Mediterranean diet and a home-based exercise plan or to a waitlist group that won’t make any changes during the study. To join, you should be able to understand English or Spanish and have the approval of your oncologist. Importantly, you’ll need to have access to the internet to engage with the study materials. This trial aims to support lymphoma survivors in their recovery journey, so if you think you might be interested, it could be a great opportunity to enhance your health during treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. 18 years of age or older
• • 2. Any sex/gender
• • 3. Able to provide consent
• • 4. Able to read or understand English or Spanish
• 5. Diagnosis of untreated Non-Hodgkin or Hodgkin lymphoma, requiring at least 6 cycles of chemotherapy, being treated with one of the following therapies at discretion of PIs:
• • 1. R-CHOP or R-CHOP-like regimen
• • 2. BR
• • 3. BV-AVD or ABVD or checkpoint inhibitor+AVD
• • 6. ECOG Performance Status grade of \<2
• • a. PI approval needed if ECOG = 2
• • 7. Approval from treating oncologist, confirmed via email or in writing
• 8. Delivery of chemotherapy treatments at one of the following institutions:
• • 1. Sylvester Comprehensive Cancer Center (including satellite/network sites)
• • 2. University of Miami Hospital/UHealth Tower
• • 9. Internet access on a smart phone, tablet, or computer
• • 10. Willing to be randomized to a Mediterranean diet/home-based physical activity intervention or waitlist-control group.
• Exclusion Criteria:
• • 1. Individuals younger than 18 years of age
• • 2. Unable to provide consent
• • 3. Unable to read or understand English or Spanish
• • 4. Any contraindication for diet change or exercising as determined by physician
• • 5. Currently following a vegan or ketogenic diet, or consuming more than 5 servings of fruit and vegetables per day for the prior month
• • 6. Engaging in \>150 minutes of moderate to vigorous physical activity on average per week for the prior month
• • 7. History of dementia or major psychiatric disease
• • 8. History of recent (≤1 yr) stroke, myocardial infarction or congestive heart failure