Hyperbaric Oxygen Therapy for Men Suffering From Infertility Due to Oligospermia.

Launched by ASSAF-HAROFEH MEDICAL CENTER · Apr 24, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the effects of Hyperbaric Oxygen Therapy (HBOT) on men who are experiencing infertility due to a condition called oligospermia, which means having a low sperm count. Infertility affects many couples trying to conceive, and this study aims to see if HBOT can help improve sperm counts in men diagnosed with this condition. The trial is currently recruiting participants who are male, at least 21 years old, and have had at least two sperm tests showing low sperm counts.

To participate, men must be willing to attend regular clinic visits and understand the study's requirements. However, there are some criteria that would exclude a person from joining, such as having a serious illness, a history of certain cancer treatments, or existing health issues that could complicate the therapy. If eligible, participants can expect to receive HBOT, which involves breathing pure oxygen in a specially designed chamber, and they will be monitored throughout the study to assess any changes in their sperm count.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Age above 21 years
• • 2. At least two sperm examination showing oligospermia (\<15·106 sperm/mL)
• • 3. Diagnosis of idiopathic oligospermia.
• • 4. Subject willing and able to read, understand and sign an informed consent
• Exclusion Criteria:
• • 1. Inability to attend scheduled clinic visits and/or comply with the study protocol
• • 2. Active malignancy
• • 3. Previous treatment with chemotherapy and/or radiation therapy
• • 4. Substance use at baseline
• • 5. Severe or unstable physical disorders or major cognitive deficits at baseline
• • 6. HBOT for any reason prior to study enrolment
• • 7. Chest pathology incompatible with pressure changes (including moderate to severe asthma)
• • 8. Ear or Sinus pathology incompatible with pressure changes
• • 9. Chronic disease like diabetes mellitus, ischemic heart disease etc.
• • 10. Active smoking