RefleXion PET/CT Imaging Performance in Patients With Various Malignancies

Launched by CITY OF HOPE MEDICAL CENTER · May 3, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging system called the RefleXion Medical Radiotherapy System (RMRS) to see how well it works compared to the standard imaging method known as PET-CT scans in patients with different types of cancer. PET-CT scans use a small amount of a radioactive substance to highlight cancer cells, allowing doctors to see where the cancer is in the body. The goal of this trial is to determine if the RMRS can improve the quality of imaging and help plan radiation therapy more efficiently, potentially reducing the number of scans needed.

To participate in this trial, patients must be at least 21 years old and have been diagnosed with various cancers, such as tumors in the abdomen, pelvis, chest, head, neck, or breast. They should already be scheduled for a standard PET-CT scan before joining the study. It's important to note that individuals with certain psychiatric or substance abuse issues, those who weigh more than 450 pounds, and patients with specific tumor types will not be eligible for this trial. Participants can expect to undergo imaging using the new system and contribute to research that could enhance cancer treatment in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Documented informed consent of the participant and/or legally authorized representative
• • Age: \>= 21 years
• • Patients with malignancies (abdominal/pelvic/thoracic/head and neck/breast tumors) undergoing SOC \[18F\]-FDG PET-CT for diagnostic and/or radiotherapy planning purposes
• • Patients should be scheduled for \[18F\]-FDG PET-CT prior to study entry
• Exclusion Criteria:
• • Known psychiatric or substance abuse disorder that would interfere with conduct of the study
• • Patient weight exceeding the weight limit (450 pounds) outlined per X1 RMRS specifications sheet
• • Lung parenchymal and bone tumors will be excluded as their imaging characteristics were evaluated in a previous study