Effects of Remote Ischemic Conditioning on Blood Pressure in Older Patients With Hypertension

Launched by YI YANG · Apr 26, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a method called remote ischemic conditioning to see how it affects blood pressure in older patients with essential hypertension, which is a common form of high blood pressure. The trial is looking for participants aged between 65 and 85 who have a history of high blood pressure, with a systolic blood pressure of 140 mmHg or higher. This means that if you or a loved one fits this age range and has been diagnosed with high blood pressure, you might be eligible to join the study.

If you decide to participate, you will undergo a procedure that is designed to safely stimulate blood flow in a way that may help lower your blood pressure. The researchers are currently recruiting participants, and you will need to sign a consent form to join. However, people with certain medical conditions, such as severe organ dysfunction or a recent heart-related event, will not be eligible. This study aims to find a new way to help manage high blood pressure in older adults, which is important for overall health and wellbeing.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1) Age ≥65 years and ≤85 years, regardless of gender;
• • 2) History of essential hypertension and clinical systolic blood pressure ≥ 140 mmHg, regardless of whether they are receiving antihypertensive medication;
• • 3) Willing to participate and sign the informed consent.
• Exclusion Criteria:
• • 1) Secondary hypertension;
• • 2) Clinical blood pressure ≥ 180/110 mmHg or 24-hour mean arterial pressure ≥ 170/100 mmHg;
• • 3) Severe organ dysfunction or failure;
• • 4) Severe hematologic disorders or significant coagulation abnormalities;
• • 5) History of atrial fibrillation or myocardial infarction within 6 months;
• • 6) Individuals who had contraindication of remote ischemic conditioning, such as severe soft tissue injury, fracture or vascular injury in the upper limb, acute or subacute venous thrombosis, arterial occlusive disease, subclavian steal syndrome, etc;
• • 7) Individuals who will or have received anticoagulant therapy with drugs such as dabigatran, rivaroxaban, warfarin, etc;
• • 8) Those who are participating in other clinical research or has participated in other clinical research or has participated in this study within 3 months prior to enrollment;
• • 9) Other conditions that the researchers think are not suitable for the project.