Profiles of Urinary Tract Infections in General Practice

Launched by CNGE CONSEIL · Apr 26, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at urinary tract infections (UTIs), which are common infections that can affect many people. The study aims to understand different types of UTI cases that may not be just the usual bladder infections (cystitis) or kidney infections (pyelonephritis). Researchers believe that there might be other forms of UTIs that require longer treatments and want to identify what factors might influence this.

To be eligible for the trial, participants should be at least 18 years old and have symptoms that suggest a UTI, such as fever, painful urination, or changes in urine appearance. Those over 70 may also have specific symptoms like sudden confusion. Participants will be asked to join the study after learning about what it involves. This research is important because it can help improve how UTIs are treated, especially in a time when antibiotic resistance is a growing concern. If you or a loved one experiences these symptoms and meet the criteria, this study could offer valuable insights while also contributing to better healthcare practices.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient ≥18 years old
• * Patient presenting one or more of the following clinical signs suggestive of urinary tract infection in general practice consultation:
• • fever (temperature \> 38°C)
• • chills, sweats
• • burning urination
• • urinary urgency
• • pollakiuria
• • dysuria
• • lumbar and/or pelvic pain
• • abnormal urine appearance: cloudy, malodorous, macroscopic haematuria
• • absence of leucorrhoea
• * specifically in people \> 70 years old:
• • recent onset urinary incontinence
• • sudden confusion
• • bladder globe
• • Positive urine dipstick and/or positive Cytobacteriological Examination of Urine (CBEU)
• • Patient affiliated with the French National Health Insurance or beneficiary of such a scheme.
• • Patient's oral non-opposition of participation in the study after receiving complete information about the protocol
• Non-inclusion Criteria:
• • Patient \< 18 years old
• • Declared pregnancy
• • Patient with indwelling urinary catheter
• • Patient with functional or organic abnormality of the urinary tract
• • Patient with known severe immunodeficiency (HIV+ with CD4 count \< 200/mm3, organ transplant, bone marrow transplant, patient on immunosuppressants, cirrhosis)
• • Patient with known severe chronic renal failure (clearance \< 30 mL/min)
• • Patient previously treated with an antibiotic (for an other reason than a urinary tract infection and/or treatment failure of the urinary tract infection) in the past month before the inclusion consultation
• • Patient speaking little or no French
• • Patient with severe cognitive impairment
• • Patient with life expectancy \< 3 months
• • Patient under legal protection, inability to give an oral non-opposition
• • Patient with severity criteria justifying hospitalization