Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study

Launched by UNIVERSITY MEDICAL CENTER GRONINGEN · May 5, 2023

Keywords

ClinConnect Summary

**Clinical Trial Summary: Breast Cancer Long-Term Outcomes on Cardiac Functioning**

This clinical trial is studying how breast cancer treatments, like chemotherapy and radiotherapy, might affect heart health in women who survived breast cancer. Researchers want to find out if these survivors are at risk of developing long-term heart problems, specifically focusing on how well the heart pumps blood. They aim to determine whether doctors should monitor the heart health of these patients more closely and identify which survivors might be at greater risk for heart issues.

To participate in the study, you must be a woman who was diagnosed with breast cancer at least 11 years ago and received treatments like chemotherapy or radiotherapy. If you took part in the previous BLOC-I study, you are eligible to join. Participants will undergo tests to assess their heart function, and this will help researchers understand if there are any signs of heart problems. The trial is currently recruiting participants, and while it's important to stay informed about your heart health after cancer treatment, this study aims to provide clearer guidance for doctors on how to support breast cancer survivors in the long run.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• * Patients who previously took part in de BLOC-I study will be included. These criteria were:
• • females diagnosed with stage I-III BC at least five years ago or local or locoregional recurrence of BC at least five years ago
• • treatment with chemotherapy and/or radiotherapy.
• Exclusion Criteria:
• • Patients unfit to travel to the hospital due to severe mental or physical illness, based on assessment by their GP.
• Exclusion criteria for the BC survivors in the BLOC-I study were:
• • metastatic disease at the time of BC diagnosis;
• • BC treatment after 80 years of age;
• • history of treatment for other types of cancer.