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Search / Trial NCT05852145

Oral Changes With Caloric and no Caloric Sweeteners

Launched by HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ · May 5, 2023

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Artificial Sweetener Stevioside P H Caries Sucrose Dental Biofilm

ClinConnect Summary

This clinical trial is looking at how different types of sweeteners in drinks affect oral health, specifically focusing on pH levels (which indicate acidity) and the types of bacteria in dental plaque, in Mexican teenagers. Participants will drink three different types of beverages on separate occasions: one without any sweeteners, one with a non-caloric sweetener called stevioside, and one with a sugary sweetener called sucrose. The researchers will then compare how each drink changes the acidity in saliva and dental plaque, as well as the growth of bacteria in the mouth.

To be eligible for this study, participants should be teenagers who usually drink soft drinks and have a certain level of dental issues (indicated by the Decayed, Missing, and Filled Teeth index). They must also get permission from their parents to join. However, those currently undergoing orthodontic treatment, using fluoride treatments, or who have certain health conditions affecting their ability to brush their teeth won't be able to participate. If you join the study, you can expect to drink the different beverages and help researchers learn more about how what we consume affects our oral health.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Habitual consumption of soft drinks
  • Decayed, Missing, and Filled Teeth (DMF) index of at least 3 (considering as caries those lesions that are visible without the tooth needing to be dry)
  • Agree to participate in the study and sign informed consent
  • Parents sign informed consent
  • Any nutritional condition
  • Exclusion Criteria:
  • Orthodontic treatment
  • Topical application of fluoride during the last 3 months
  • Having a motor disability that interfered with tooth brushing
  • Xerostomia
  • Antibiotic therapy during the study period
  • Periodontal infections

About Hospital Infantil De Mexico Federico Gomez

Hospital Infantil de México Federico Gómez is a leading pediatric healthcare institution dedicated to advancing the field of child health through innovative clinical research and comprehensive patient care. As a prominent sponsor of clinical trials, the hospital focuses on developing and evaluating new treatments and therapies to improve health outcomes for children. With a commitment to excellence, the institution combines clinical expertise with rigorous scientific methodology, fostering collaboration among healthcare professionals, researchers, and academic partners to address pressing pediatric health challenges. Its mission is to enhance the quality of life for children through cutting-edge research and compassionate care.

Locations

Patients applied

0 patients applied

Trial Officials

Carolina Barajas, MsC

Principal Investigator

Children´s Hospital Federico Gómez. México

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported