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Search / Trial NCT05853887

Liquid Biopsy Based NGS in Newly Diagnosed NSCLC

Launched by CHARU AGGARWAL · May 9, 2023

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Next Generation Sequencing Liquid Biopsy Newly Diagnosed Molecular Testing Plasma Based Next Generation Sequencing Electronic Health Record Nudge Intervention Targeted Therapy Behavioral Economics

ClinConnect Summary

This clinical trial is looking at a method called "liquid biopsy" to help doctors make better treatment decisions for patients with a specific type of lung cancer known as metastatic non-squamous non-small cell lung cancer (NSCLC). The trial aims to encourage doctors to order important molecular tests right after a patient is diagnosed, so they can have the results before starting any treatment. This way, doctors can tailor the treatment based on the unique characteristics of the cancer, leading to potentially better outcomes. The study is also interested in understanding what helps or hinders the successful use of this method in clinical practice.

To participate in this trial, you must be diagnosed with metastatic non-squamous NSCLC and have not yet started treatment. Additionally, you need to be seen at one of the participating hospitals in the Lancaster area or nearby locations. Unfortunately, those with incomplete staging information or certain other conditions, such as children and pregnant women, cannot join the study. If you qualify and choose to participate, you'll help researchers learn more about improving lung cancer treatment while also gaining access to valuable testing that can guide your care.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants with a histological, or cytological diagnosis of metastatic non-squamous (mNSq) non-small cell lung cancer (NSCLC) who have not yet received systemic treatment for metastatic disease.
  • Participants must be seen at Lancaster General Health (LGH), Penn Presbyterian Medical Center (PPMC), Penn Medicine Cherry Hill (PMCH), Penn Medicine Princeton Health (PMPH), Penn Medicine Voorhees (PMV) or Penn Medicine Washington Township (PMWT) for mNSq NSCLC.
  • Exclusion Criteria:
  • Participants with incomplete staging information.
  • Children, pregnant women, fetuses, neonates, or prisoners are not included in this research study.

About Charu Aggarwal

Charu Aggarwal is a distinguished clinical trial sponsor known for her commitment to advancing medical research and improving patient outcomes. With a strong background in oncology and clinical trial design, she leads initiatives that focus on innovative therapeutic approaches and evidence-based practices. Her leadership fosters collaboration among multidisciplinary teams, ensuring rigorous adherence to regulatory standards and ethical considerations throughout the research process. Charu's expertise not only enhances the quality of clinical trials but also contributes to the development of novel treatments that address unmet medical needs, positioning her as a vital contributor to the field of clinical research.

Locations

Plainsboro, New Jersey, United States

Philadelphia, Pennsylvania, United States

Lancaster, Pennsylvania, United States

Cherry Hill, New Jersey, United States

Sewell, New Jersey, United States

Voorhees, New Jersey, United States

Patients applied

0 patients applied

Trial Officials

Charu Aggarwal, MD, MPH

Principal Investigator

Penn Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported