The Recurrence Mechanism of Venous Tinnitus After Boney Wall Reconstruction Based on Multimodal Imaging and Multiphysics Coupling
Launched by BEIJING FRIENDSHIP HOSPITAL · May 3, 2023
Trial Information
Current as of July 01, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating the reasons why some patients experience a return of venous tinnitus (VT) after undergoing surgery to reconstruct the bony wall around their sinus. VT is a condition where people hear a rhythmic noise that matches their heartbeat, and it affects many individuals in China. The researchers believe that changes in the structure and blood flow around the sinus after surgery may contribute to the recurrence of this condition. To explore this, they will use advanced imaging techniques and computer models to understand how different factors, like blood flow and pressure, could influence whether or not VT comes back after surgery.
If you're considering participating in this trial, you may be eligible if you have been diagnosed with venous tinnitus, have normal ear examinations, and have specific findings from CT scans that show problems with your sinus wall. Participants will undergo various imaging tests and provide data to help researchers identify what might cause VT to recur. The goal is to develop personalized treatment plans that could help prevent VT from returning after surgery. This study is currently recruiting participants of all ages, so if you meet the criteria and are interested, it could be a valuable opportunity to contribute to improving treatment for this condition.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients with venous tinnitus, a rhythmic noise that follows the heart beating without external stimuli and can disappear or significantly reduce after compression of the affected side of the neck
- • the normal otoscopy
- • venous tinnitus patients with confirmed sigmoid sinus wall dehiscence with or without sigmoid sinuses enlargement, diverticula and transverse sinuses stenosis using dual-phase enhanced CT examination
- • preoperative DSA examination
- • bone wall reconstruction
- Exclusion Criteria:
- • contraindications for CT and MR Examination
- • tumor and arterial abnormalities
About Beijing Friendship Hospital
Beijing Friendship Hospital, affiliated with Capital Medical University, is a leading comprehensive medical institution located in Beijing, China. Renowned for its advanced clinical services and cutting-edge research, the hospital plays a pivotal role in promoting healthcare innovation and improving patient outcomes. As a prominent clinical trial sponsor, Beijing Friendship Hospital is committed to conducting high-quality, ethical research that adheres to international standards. The hospital's multidisciplinary teams leverage their expertise across various medical fields to facilitate the development of new therapies and interventions, ultimately contributing to the advancement of medical science and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Beijing, Beijing, China
Patients applied
Trial Officials
Zhenchang Wang, Prof.
Principal Investigator
Beijing Friendship Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported