Maternal Choline Supplementation and Offspring Cognition in Adolescence
Launched by CORNELL UNIVERSITY · May 12, 2023
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Eggs are one of the richest dietary sources of choline, an essential nutrient that plays critical roles in fetal development, including shaping the structure and function of the offspring brain. Furthermore, evidence shows that pregnancy dramatically increases the demand for choline.
In rodents consuming standard chow, pregnancy results in a pronounced depletion of maternal choline pools, indicating that choline requirements during pregnancy are increased and that maternal and fetal requirements likely exceed the amount typically consumed by mothers. Additionally, human research from the i...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Offspring of mothers from the original choline feeding trial
- • Testing will commence when the child reaches 13 years of age (determined by date of birth of participant)
- Exclusion Criteria:
- • Failure to follow the study protocol regarding test procedures and questionnaires
- • Lack of internet access with the requisite speed and stability needed to support the online testing tools
About Cornell University
Cornell University is a prestigious Ivy League institution renowned for its commitment to academic excellence and innovative research. As a clinical trial sponsor, Cornell leverages its interdisciplinary expertise and state-of-the-art facilities to advance medical knowledge and improve patient outcomes. The university fosters collaboration among leading researchers, clinicians, and students, aiming to translate scientific discoveries into effective therapies. Cornell's rigorous adherence to ethical standards and regulatory compliance ensures the integrity and safety of its clinical trials, contributing to the advancement of healthcare and the well-being of communities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ithaca, New York, United States
Patients applied
Trial Officials
Barbara Strupp, PhD
Principal Investigator
Cornell University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported