Acute Cardiac Dysfunction in Critical Illnes

Launched by SAHLGRENSKA UNIVERSITY HOSPITAL · May 8, 2023

Keywords

ClinConnect Summary

**Summary of the Clinical Trial: Acute Cardiac Dysfunction in Critical Illness**

This clinical trial is investigating how heart problems affect critically ill patients who are experiencing multi-organ failure. The researchers want to understand how common these heart issues are and how they impact patients both in the short term (like during their hospital stay) and in the long term (after they leave the hospital). They will also look into what causes these heart problems and identify important factors related to them.

To participate in this trial, individuals must be over 18 years old and admitted to an intensive care unit (ICU) within the last 24 hours, showing signs of significant organ dysfunction, which means their bodies are having trouble with at least two different organ systems. Participants will need to give their consent or have it provided by a family member if they are unable to do so. If you or a loved one are eligible, you can expect to undergo tests that include echocardiograms (a type of heart ultrasound) within the first day of being in the study. The trial is currently recruiting participants, and all genders are welcome to join.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged \> 18 years
• • 2. Admitted to a participating ICU within 24 hours
• 3. Significant organ dysfunction involving at least two organ systems. This is defined as fulfilling both of the following:
• • At least 4 points on the SOFA scale (Sequential Organ Failure Assessment scale)
• • Having at least 1 point on the SOFA scale from at least two organ systems
• • 4. Given informed consent from patient or permission to participate from next of kin
• Exclusion Criteria:
• • 1. Echocardiographic examination not possible (e.g., pneumothorax, draping etc) or very low echocardiographic examination quality
• • 2. Not being examined with echocardiography within 24 hours from inclusion
• • 3. Retracted consent to participate