Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth
Launched by CAIRO UNIVERSITY · May 6, 2023
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating the effectiveness of cinnamon extract compared to sodium hypochlorite, a common dental disinfectant, as a treatment during a specific procedure called pulpectomy. This procedure is performed on children who have serious tooth issues, such as irreversible pulpitis (inflammation of the tooth's inner tissue) and cavities in their primary (baby) molars. The main goal is to see which of these treatments can better reduce bacteria in the tooth after the procedure.
To be eligible for this study, children aged 4 to 8 years old must be in good health and able to cooperate during dental treatments. Their teeth should have signs of serious decay and pain, and they should not have taken antibiotics recently. Parents will need to provide written consent for their children to participate. If enrolled, participants can expect to receive either the cinnamon extract or sodium hypochlorite as part of their treatment, and their dental health will be monitored throughout the study. This research may provide valuable insights into alternative treatments for dental issues in young children.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- * Children:
- • 1. Aged 4 to 8, in good general health, and medically free.
- • 2. Cooperative patients who will comply to dental treatment .
- • 3. Parents provided with written informed consent.
- • 4. No previous history of antibiotics administration or last dose was taken from at least 2 weeks.
- * Teeth:
- • 1. Carious primary molars with irreversible pulpitis.
- • 2. Presence of localized swelling ,sinus and pain on percussion which indicate non vital pulp .
- • 3. Presence of periapical and furcation radiolucency .
- • 4. In periapical radiograph teeth have no more than 1/3 of root resorption.
- Exclusion Criteria:
- * Children:
- • 1. Children with medical, physical, or mental conditions.
- • 2. Severly Uncooperative children .
- * Teeth:
- • 1. Primary molars with any congenital anomalies.
- • 2. Teeth with un-restorable crowns .
- • 3. Root resorbtion more than half of the root.
- • -
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported