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Search / Trial NCT05861973

SMARTer Weight Loss Management

Launched by NORTHWESTERN UNIVERSITY · May 8, 2023

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Stepped Care Adaptive Intervention Non Inferiority Trial Behavioral Obesity Treatment

ClinConnect Summary

The SMARTer Weight Loss Management trial is a research study looking at different ways to help people lose weight, specifically for those struggling with obesity. The trial compares a new approach called the SMARTer intervention, which provides tailored support based on individual needs, to a standard weight loss program known as the Diabetes Prevention Program (DPP), and a control group that only receives general information about weight loss. The goal is to see if the SMARTer intervention can help participants lose weight effectively while being more affordable than the standard program.

To participate in this study, you need to be over 18 years old, have a body mass index (BMI) of 25 or higher, and weigh less than 396 pounds. You’ll also need to have a smartphone and be willing to use the SMARTer app for the duration of the 12-month study. Participants should plan to live in the Chicagoland area during this time and should not be enrolled in any other weight loss program. Throughout the trial, participants will receive support and guidance to help them reach their weight loss goals, and researchers will carefully track costs and outcomes to determine the best options for weight management in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Over 18 years old
  • BMI of ≥25, weight \<396 lbs
  • Must own a Smartphone, and be willing to install the SMARTer app
  • Participants must also plan to reside in the Chicagoland area for the duration of their participation (i.e., 12 months)
  • Not enrolled in a formal weight loss program
  • Exclusion Criteria:
  • Cerebrovascular accident or myocardial infarction within six months of enrollment
  • Diabetes treated with insulin
  • Pregnancy, lactation or intended pregnancy
  • Active suicidal ideation
  • Anorexia or bulimia
  • Requiring an assistive device for mobility
  • Taking weight loss medications, such as GLP-1 agonists

About Northwestern University

Northwestern University is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a robust infrastructure that supports interdisciplinary collaboration, Northwestern leverages its expertise in various fields, including medicine, engineering, and social sciences, to drive groundbreaking studies. The university is dedicated to adhering to the highest ethical standards and regulatory compliance, ensuring that all clinical trials are conducted with the utmost integrity and focus on participant safety. Through its Clinical Trials Office, Northwestern aims to translate scientific discoveries into effective therapies, ultimately enhancing health outcomes and contributing to the broader medical community.

Locations

Chicago, Illinois, United States

Patients applied

CK

1 patients applied

Trial Officials

Bonnie Spring, PhD

Principal Investigator

Northwestern University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported