REtinal Detachment Outcomes Study

Launched by CHU DE QUEBEC-UNIVERSITE LAVAL · May 16, 2023

Keywords

ClinConnect Summary

The REtinal Detachment Outcomes Study is a clinical trial designed to find the best surgical methods for treating a specific type of eye condition called rhegmatogenous retinal detachment (RRD). This study will compare two surgical techniques: one that uses a method called pars plana vitrectomy (PPV) alone and another that combines PPV with a scleral buckle (PPV-SB). Additionally, the study will look at two types of gas used during the surgery: sulfur hexafluoride (SF6) and perfluoropropane (C3F8). Researchers want to learn which combination of these techniques and gases leads to the best results in terms of the eye healing properly, improving vision, and minimizing complications over a year after surgery.

To participate, individuals must be at least 18 years old and diagnosed with RRD. However, some conditions, like certain types of severe retinal issues or previous eye surgeries, may prevent someone from joining. Participants will undergo surgery and be monitored for a year using various imaging techniques and questionnaires to assess their recovery and quality of life. This trial is significant because it aims to provide new insights that can help doctors make better treatment decisions for patients with RRD, based on strong evidence rather than past experiences or smaller studies.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years
• • Diagnosis of rhegmatogenous retinal detachment
• Exclusion Criteria, retinal detachment with:
• • Proliferative vitreoretinopathy (PVR) grade ≥C2
• • Chronic RRD with duration \>3 months
• • Proliferative diabetic retinopathy with tractional retinal detachment (RD)
• • Macular holes
• • Epiretinal membrane grade 3 or 4
• • Traumatic RD
• • Giant retinal tears
• • Retinal dialysis
• • Foveoschisis
• • Wet age-related macular degeneration
• • Endophthalmitis
• • Acute retinal necrosis
• • Coats disease
• • Retinopathy of prematurity
• • Retinoschisis
• • Retinal colobomas
• • Prior glaucoma surgery or strabismus surgery (favoring PPV only)
• • Superior RD extent less than 3 clock hours (favoring PPV only)