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Search / Trial NCT05864521

Beetroot Juice and Sleep

Launched by MAYO CLINIC · May 9, 2023

Trial Information

Current as of August 20, 2025

Recruiting

Keywords

Blood Pressure Sleep

ClinConnect Summary

This clinical trial is looking at how drinking beetroot juice, which is high in a substance called inorganic nitrate, might affect sleep and brain blood flow. Researchers want to understand if this natural supplement can help improve sleep quality and overall brain function. The study is currently recruiting participants aged between 18 to 35 and 65 to 80 years old, and anyone interested in joining should not have certain health conditions, like heart problems, diabetes, or sleep disorders.

If you decide to participate, you'll be asked to drink beetroot juice and take part in some assessments related to sleep and brain health. It’s important to note that individuals who smoke, have recently traveled across multiple time zones, or have a high body weight may not be eligible for this study. This trial could provide valuable insights into how a simple dietary change might influence sleep and brain function, so if you fit the criteria and are interested, it might be worth considering!

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18-35 or 65-80 years of age
  • Exclusion Criteria:
  • Coronary artery disease
  • Heart failure
  • Pregnancy
  • Diabetes
  • Sleep disorders
  • Shift workers
  • Individuals who typically go to sleep after midnight
  • Individuals who traveled across ≥2 time zones within one week of study visits
  • Individuals with a history frequent kidney stones
  • BMI ≥35.0kg/m2
  • Use of nicotine-containing products within the two years preceding study visits
  • Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with the nitrate-nitrite-nitric oxide pathway or outcome measures

About Mayo Clinic

Mayo Clinic is a renowned nonprofit medical practice and research institution dedicated to providing comprehensive healthcare and advancing medical knowledge through innovative research and education. With a commitment to patient-centered care, Mayo Clinic conducts numerous clinical trials aimed at exploring new therapies and improving treatment outcomes across various disciplines. Leveraging a multidisciplinary approach, the institution collaborates with leading experts and cutting-edge technology to ensure rigorous scientific standards and ethical practices in all its research endeavors. Through its trials, Mayo Clinic seeks to translate breakthroughs in science into tangible benefits for patients, fostering advancements in medicine that enhance health and quality of life.

Locations

Rochester, Minnesota, United States

Patients applied

0 patients applied

Trial Officials

Virend Somers, MD, PhD

Principal Investigator

Mayo Clinic

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported