Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

Launched by WASHINGTON UNIVERSITY SCHOOL OF MEDICINE · May 8, 2023

Keywords

ClinConnect Summary

This clinical trial is looking into a new way to help doctors plan surgery for patients with glioblastoma multiforme, a type of brain cancer. Researchers are using advanced computer technology to analyze brain scans taken before surgery. The goal is to see if this technology can predict how well a patient's tumor will respond to treatment, which could help doctors make better decisions about care.

To participate in this study, you need to be at least 18 years old and have a diagnosis of a brain lesion that looks like glioblastoma multiforme. You’ll need to be planning to have a special brain scan called an MRI before your surgery. Participants can expect to have their MRI analyzed using this new computer algorithm, and they will be asked to sign a consent form to ensure they understand the study. It's important to know that if you cannot have an MRI or if you won't be able to attend follow-up appointments for the study, you may not be eligible. This trial is currently recruiting participants of all genders, and it aims to improve treatment options for patients facing this challenging condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Must have a radiological diagnosis of a lesion in the brain with characteristics consistent with glioblastoma multiforme.
• • Must be planning to undergo a pre-operative MRI.
• • Must be at least 18 years old.
• • Must be able to understand and willing to sign an IRB approved written informed consent document.
• Exclusion Criteria:
• • Contraindication to MRI.
• • Inability to have clinical follow-up (e.g., patient is out of town and will do follow-up elsewhere).