Profile of Dysphagia in Myotonic Dystrophy Type 1 (DM1)

Launched by UNIVERSITY COLLEGE, LONDON · May 9, 2023

Keywords

ClinConnect Summary

This clinical trial, called the "Profile of Dysphagia in Myotonic Dystrophy Type 1," is focused on understanding swallowing difficulties, known as dysphagia, in people with myotonic dystrophy type 1 (DM1). Researchers want to find out if the muscles that help us swallow are different in size and structure for those with DM1 compared to those without the condition. They also aim to understand how these muscle differences might affect people’s ability to swallow and any related symptoms they might experience.

To participate in this study, you need to be at least 18 years old and have a confirmed diagnosis of DM1. You should also be able to drink at least five sips of liquid in one go. Participants will undergo several tests, including an ultrasound to look at the swallowing muscles, an x-ray study to observe swallowing, and questionnaires about swallowing symptoms and overall well-being. The study is currently recruiting and welcomes individuals of all genders who meet the eligibility criteria. This research could provide valuable insights into how DM1 affects swallowing, which can ultimately help improve care for those living with the condition.

Gender

ALL

Eligibility criteria

• • Participants with DM1
• Inclusion:
• • ≥18 years of age
• • genetically confirmed of DM1
• • able to eat \& drink at least five sips of liquid by mouth at one time.
• Exclusion:
• • any condition or treatment other than DM1 that potentially influences swallowing muscle composition or function (e.g., a history of stroke or throat cancer).
• • any patients who are pregnant
• • patients with congenital or childhood DM1
• • patients who are not able to eat or drink anything by mouth.