Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy

Launched by OSLO UNIVERSITY HOSPITAL · May 18, 2023

Keywords

ClinConnect Summary

**Summary of the Clinical Trial: Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy**

This clinical trial is exploring a new, non-invasive device that helps doctors evaluate how well a treatment called cardiac resynchronization therapy (CRT) works for patients with certain heart conditions, particularly those with a specific heart rhythm problem known as left bundle branch block (LBBB). CRT can be a significant help for patients with heart failure, but unfortunately, not everyone benefits from it. The study aims to see if this device can provide useful information during the procedure and at follow-up visits, along with using ultrasound to observe changes in heart function when the CRT is turned on and off.

To participate in this trial, patients should be between 18 and 80 years old and have been diagnosed with heart failure, specifically in classes II or III, meaning their heart condition is moderate to severe. They must have a good understanding of their heart rhythm and have had a specific test called echocardiography before the procedure. Participants will receive the CRT device and undergo assessments to see how their heart responds to the treatment. This trial is currently recruiting participants at Oslo University Hospital, and everyone involved will need to give their consent to take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients referred for CRT implantation or postoperative control at Oslo University Hospital based on the European Society of Cardiology (ESC) guidelines (2021), and criteria below:
• • 1. Sinus rhythm.
• • 2. New York Heart Association class II / III heart failure on diagnosis and on optimal medical therapy.
• • 3. Left bundle branch block.
• • 4. QRS duration ≥ 130 ms.
• • 5. Left ventricular ejection fraction ≤ 40%.
• • 6. Patients must have echocardiography examination before implantation
• • 7. Informed consent obtained from the patient.
• Exclusion Criteria:
• • 1. Age \< 18 years and \> 80 years;
• • 2. Ongoing atrial fibrillation;
• • 3. Complete atrioventricular block