ClinConnect ClinConnect Logo
Search / Trial NCT05871216

Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility

Launched by ISTITUTO ORTOPEDICO RIZZOLI · May 12, 2023

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at how people with Joint Hypermobility Syndrome (JHS) maintain their balance and stability. JHS is a condition where joints are more flexible than normal, which can lead to pain and other issues. The study will use a special balance test to see how well patients can maintain their posture while standing on one leg or both legs. This is important because understanding balance can help improve everyday activities and sports performance for those with this condition.

To participate in the trial, individuals should be between the ages of 6 and 74 and have either moderate to severe joint hyperlaxity, which is assessed using a specific scoring system. However, people with obesity, certain medical conditions, or who are involved in competitive sports will not be eligible. Participants can expect to take part in balance tests and contribute to a better understanding of how JHS affects stability, which could help develop better treatments or support for others with similar conditions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with moderate (Beighton-Horan Joint Mobility Index score from 3 to 4) or severe (Beighton-Horan Joint Mobility Index score from 5 to 9) joints hyperlaxity at the clinical evaluation
  • Exclusion Criteria:
  • Obesity (BMI \> 25) and weight \> 90 kg
  • Practice of competitive sport
  • Orthopedic (complex surgery of the spine and lower limbs), neurological (spasticity, stroke), and oncological comorbidities
  • Orthostatic / walking inability
  • Absence of joints hyperlaxity at the clinical evaluation (Beighton-Horan Joint Mobility Index score from 0 to 2)

About Istituto Ortopedico Rizzoli

Istituto Ortopedico Rizzoli is a renowned orthopedic research and treatment institute based in Bologna, Italy, dedicated to advancing musculoskeletal health through innovative clinical trials and cutting-edge medical practices. With a strong emphasis on research, the institute collaborates with leading experts in orthopedics, rehabilitation, and related fields to develop and evaluate new therapies and surgical techniques. Committed to improving patient outcomes, Istituto Ortopedico Rizzoli not only focuses on high-quality clinical care but also fosters a robust research environment that supports the translation of scientific findings into clinical applications.

Locations

Bologna, , Italy

Patients applied

LH

1 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported