Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia

Launched by CHULALONGKORN UNIVERSITY · May 22, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a new type of artificial saliva that contains extracts from cumin and ginger. It aims to see if this special saliva can help patients with head and neck cancer who are experiencing dry mouth, a condition known as xerostomia. The study will evaluate both how effective this treatment is and how safe it is for patients.

To be eligible for this trial, participants must be adults over 18 years old who have had head and neck cancer and have been dealing with dry mouth for at least six months after their radiation treatment. However, individuals with certain conditions, such as specific types of salivary gland problems or those currently on certain medications for dry mouth, won’t be able to participate. If you decide to join the study, you will be monitored to see how well the artificial saliva works for you, and your safety will be a priority throughout the trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age more than 18 years
• • Head and neck cancer with xerostomia
• • 6 months post radiation
• • Willing to participate in this study
• Exclusion Criteria:
• • Sialolith or Sjogren's syndrome
• • Uncontrolled cancer
• • Using artificial saliva more than 2 weeks
• • Taking Pilocarpine or cevimeline more than 2 weeks
• • Allergic to cumin, ginger, xylitol, and glycerin
• • History of other oral mucosal diseases
• • Pregnancy and lactation