Sleep and Memory Consolidation in Adults With Attention Deficit Hyperactivity.

Launched by UNIVERSITY HOSPITAL, TOULOUSE · May 16, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how sleep affects memory in adults who have Attention Deficit Hyperactivity Disorder (ADHD). Researchers want to understand the differences in sleep patterns between adults with ADHD and those who are healthy. They will use a special test called polysomnography, which records brain activity during sleep, to look at how well sleep helps with memory in these individuals.

To be eligible for this study, participants need to be between 18 and 45 years old and be part of the French healthcare system. Those with ADHD must meet specific diagnostic criteria and not be on any medication for their condition. Healthy volunteers must not have any issues with sleep or memory. Participants can expect to undergo sleep testing, where their brain activity will be monitored overnight. It's important to note that individuals with certain health conditions, like untreated sleep apnea or major depression, cannot participate. This study aims to provide insights that could help improve understanding and treatment of sleep issues in people with ADHD.

Gender

ALL

Eligibility criteria

• Inclusion Criteria for all participants:
• • Age from 18 to 45 years old
• • Affiliated to the French health care system
• Inclusion Criteria for attention deficit hyperactivity disorder patients:
• • meeting Diagnostic and Statistical Manual (DSM)-5 criteria for mixed attention deficit hyperactivity disorder presentation without drug treatment for attention deficit hyperactivity disorder.
• Exclusion Criteria for all participant:
• • People not able to give consent, neurological disease (other than neurodevelopmental disorders; or any other serious disease (cancer, addiction, systemic disease)), untreated sleep apnea, major depression (Beck inventory \> 15), untreated restless leg syndrome; pregnancy in progress or wish to become pregnant during the study or breastfeeding woman, drug treatment including benzodiazepine, neuroleptic or antidepressant before inclusion.
• Exclusion Criteria for healthy volunteers:
• • Subjective cognitive and/or sleep complaint.