Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Launched by VA OFFICE OF RESEARCH AND DEVELOPMENT · May 25, 2023
Trial Information
Current as of August 19, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is designed to study how obesity affects older Veterans who have had COVID-19 or are experiencing ongoing symptoms related to the virus. Researchers want to see if a weight loss program, which includes changes in diet and exercise, can help improve physical function, quality of life, and reduce inflammation in the body. The goal is to find out if losing weight can help these Veterans recover better from Post-COVID Conditions.
To participate in this study, you need to be a U.S. Veteran, either without any lingering COVID-19 symptoms or with at least one symptom that has lasted longer than four weeks. You should also have a Body Mass Index (BMI) within a specific range, which helps measure whether someone is considered underweight, normal weight, or obese. Participants can expect to be part of a program that focuses on healthy eating and physical activity, and they will be monitored for changes in their health. If you have certain medical conditions or are on specific medications, you may not be eligible for this study.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. U.S. Veteran
- • 2. Self-reported COVID-19 naïve or COVID-19 \> 90 days ago for lean and obese PCC naïve or documented COVID-19 for the lean and obese PCC groups (At least one PCC symptom \>4 weeks)
- • 3. Body Mass Index: 19-25 or 30-50 kg/m2
- Exclusion Criteria:
- • 1. Neurologic, musculoskeletal, or other condition that limits subject's ability to complete study physical assessments
- • 2. Active inflammatory, COVID-19, autoimmune, infectious, hepatic (LFTs \> 2.5 x WNL), renal (eGFR\<45), gastrointestinal, malignant, and psychiatric disease
- • 3. Uncontrolled diabetes (HbA1c \>10% or the current use of insulin)
- • 4. Weight change within the past month of \>5 kg
- • 5. Self-reported alcohol or drug abuse
- • 6. Anti-coagulant medication usage
About Va Office Of Research And Development
The VA Office of Research and Development (ORD) is dedicated to advancing the health and well-being of veterans through innovative research initiatives. As a pivotal sponsor of clinical trials, ORD focuses on a broad spectrum of health-related topics, including mental health, rehabilitation, and chronic disease management, ensuring that findings are directly applicable to the unique needs of the veteran population. With a commitment to scientific excellence and collaboration, ORD promotes rigorous study designs and ethical standards, facilitating the translation of research discoveries into improved clinical practices and policies that enhance veteran care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Baltimore, Maryland, United States
San Antonio, Texas, United States
Patients applied
Trial Officials
Alice S. Ryan, PhD
Principal Investigator
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported