SCREaning of Advanced Liver Fibrosis Using Non-Invasive Tests in General Population

Launched by UNIVERSITY HOSPITAL, ANGERS · May 19, 2023

Keywords

ClinConnect Summary

The clinical trial titled "SCREaning of Advanced Liver Fibrosis Using Non-Invasive Tests in General Population" is focused on finding out how useful it is to screen for advanced liver fibrosis in people based on a specific blood test result called FIB4. If someone's FIB4 score is above 2.67, they may be invited for further evaluation by a liver specialist. This study aims to see if starting this screening process is beneficial for people in the general population.

To participate in this trial, you need to be between 18 and 75 years old and have had a recent blood test that shows a FIB4 score over 2.67. It’s important that your blood test results also show certain levels for other liver enzymes and platelets to ensure accuracy. If you decide to join, you will undergo a specialized evaluation to check your liver health. However, individuals who are already being treated for liver disease, pregnant women, or those who cannot provide consent due to legal reasons are not eligible to participate. This study is currently recruiting participants, so if you meet the criteria and are interested, you could play an important role in understanding liver health better!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 75 years
• • Blood sample taken at a medical testing laboratory selected for the study.
• • Biology without high risk of false positive result for FIB4 (AST and ALT ≤ 300 IU/l ; Platelets ≥ 50 G/l and \< 500 G/l.)
• • FIB4 \> 2.67 after automatic calculation in the medical laboratory less than 3 months old
• • Signature of informed consent to participate in the study
• Exclusion Criteria:
• • Ongoing specialized follow-up for a chronic liver disease
• • Difficulty understanding the French language
• • Pregnant women, breastfeeding or parturient women
• • Persons suspended from liberty by judicial or administrative decision
• • Persons under legal protection
• • Persons unable to express their consent
• • Non affiliation to a social security system