Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

Launched by INTEGRATIVE SKIN SCIENCE AND RESEARCH · May 21, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring the effects of an oral supplement called astaxanthin on skin aging. Specifically, researchers want to see if taking this supplement can help improve skin hydration (keeping skin moist), elasticity (how well skin stretches), pigmentation (color of the skin), and reduce facial redness. The study is designed so that neither the participants nor the researchers know who is receiving the astaxanthin and who is getting a placebo (a non-active treatment), which helps ensure the results are reliable.

To participate in this trial, women aged 30 to 55 are being recruited, with half having lighter skin types (Fitzpatrick skin types 1-3) and the other half having darker skin types (Fitzpatrick skin types 4-6). Potential participants should not have allergies to astaxanthin, should be willing to avoid certain foods and other supplements for a while, and must commit to a regular facial cleansing routine. Additionally, pregnant or breastfeeding women, current smokers, and those with certain medical conditions may not be eligible. If you join, you can expect to follow the study guidelines, take the supplement for a set period, and help researchers learn more about how astaxanthin might benefit skin health.

Gender

FEMALE

Eligibility criteria

• Inclusion criteria:
• • Females who are 30 to 55 years of age
• • Half of the women will have Fitzpatrick skin type 1-3 and the other half of the women will have Fitzpatrick skin type 4-6
• Exclusion criteria:
• • Individuals with a known allergy to astaxanthin or other carotenoids (such as zeaxanthin, lutein, lycopene).
• • Individuals who are unwilling to discontinue carotenoid supplementation for at least 1 month prior to enrollment
• • Individuals unwilling to restrict intake of foods like shrimp, salmon, mangos, carrots, and tomatoes during the study.
• • New supplementation within 4 weeks with tocopherol
• • Individuals who are unwilling to stay consistent with a facial cleansing regimen.
• • Those who are unwilling to discontinue topical hydroquinone, retinoid or benzoyl peroxide for 2 weeks prior to enrollment
• • Individuals who are pregnant or breastfeeding.
• • Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
• • Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years