Impact of Gonadotoxic Therapies on Fertility

Launched by MICHAEL VON WOLFF · May 22, 2023

Keywords

ClinConnect Summary

**Summary of the Clinical Trial: Impact of Gonadotoxic Therapies on Fertility**

This clinical trial is studying how certain cancer treatments, like chemotherapy, radiotherapy, and immunotherapy, can affect fertility in both men and women. Specifically, the researchers want to find out if these treatments lower hormone levels that indicate a woman’s ability to have children or decrease the number of healthy sperm in men. This research is important because it can help us understand the potential impact of cancer therapies on future family planning for patients who are undergoing these treatments.

The trial is looking for participants who are currently dealing with cancer or other non-cancer conditions that require similar treatments. Eligible participants include females aged 14-50 and males aged 18-50 from Austria, Germany, and Switzerland. Before starting treatment, participants will have a simple blood test to check hormone levels, and men will also have a sperm test. If you choose to take part in this study, you'll be helping to provide valuable information that could support others facing similar health challenges in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with cancer or with benign reasons undergoing chemotherapy and/or radiotherapy of the pelvis (females) and the testicles (males) and/or immune therapy;
• • Willing to participate;
• • Austria: 14-50 years old (adolescents and adults), Germany: 18-50 years old, Switzerland: 14-50 years old (adolescents and adults);
• • Serum hormone analysis before gonadotoxic therapy (females) or serum hormone analysis and sperm analysis before gonadotoxic therapy (males).
• Exclusion Criteria:
• • Missing consent;
• • Language barrier.