Comparison of PRP & DFDBA vs. DFDBA in Intrabony Periodontal Defects

Launched by GOVERNMENT DENTAL COLLEGE AND HOSPITAL, INDIA · May 23, 2023

Keywords

ClinConnect Summary

After being informed about the study and potential risks, 13 patients giving written informed consent and who meet the eligibility requirements were randomly allocated in a single blind manner (participants) to test group (PRP combined with DFDBA) or control group (DFDBA).

33 sites (18 test, 15 control unpaired defects) were treated - 1) to investigate the possible additional effects of PRP when combined with DFDBA, and 2) to compare the clinical and radiographic outcomes obtained in test and control groups,12 months post - operatively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Outpatients
• • with chronic periodontitis
• • who were free of local or systemic disease
• • who had not received any type of periodontal therapy in the last six months
• • radiograph showing at least one angular defect in any quadrant
• • the involved teeth were vital and asymptomatic
• • the site of interest had at least 2 mm of keratinized gingiva on the facial aspect of the selected teeth
• Exclusion Criteria:
• • Patients with abnormal platelet count
• • allergic to chlorhexidine or any other medicine used in the study
• • showing unacceptable oral hygiene compliance during / after the phase I therapy;
• • pregnant or lactating mothers;
• • smokers
• • endodontically involved teeth
• • patients under any medication known to interfere with periodontal healing. e.g., corticosteroids
• • on anticoagulant therapy
• • patients with transferable jobs or who were uncooperative
• • patients participating in other dental clinical trials.