CRT( Chemo-Radiation Therapy) Patterns and Short-term Outcomes on Unresectable NSCLC and SCLC in Routine Practices in Russia

Launched by ASTRAZENECA · May 31, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how chemotherapy and radiation therapy (together known as CRT) are used to treat patients with locally advanced non-small cell lung cancer (NSCLC) that cannot be surgically removed. The study will take place in 50 oncology centers across Russia and aims to gather information from about 6,000 patients over two years. Researchers will look at patients' medical records to learn about their treatment experiences and outcomes, including how well the CRT worked for them.

To be eligible for this trial, patients must be at least 18 years old and have given consent to participate. They should be receiving CRT for their inoperable NSCLC (which means surgery is not an option for them) and must be currently undergoing radiation treatment. Participants can expect their medical information to be collected at the beginning of their treatment and again after completing it, typically within six months. Importantly, this study will only collect information on standard treatment practices and will not involve any experimental drugs. This approach helps ensure that the study reflects real-world treatment experiences.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 18 years old
• • 2. Provision of written informed consent
• • 3. Patient received at least one RT dose under prescribed CRT (concurrent or sequential) for definitive treatment of locally advanced NSCLC (stage II-III, unresectable or inoperable NSCLC, including locoregional recurrence and patient's refusal to undergo surgery) or LS-SCLC based on local MDT decision
• • 4. Patient is currently undergoing RT (preferably no more than 10 doses)
• Exclusion Criteria:
• • 1. Participation in another clinical study with an investigational product during the last 3 months
• • 2. Confirmation that the subject was already included in this study before
• • 3. Absence of written informed consent form
• • 4. Data erroneously collected from subjects for which written consent is not available, will not be included in or will be deleted from the study database.