Clinical Significance of Adherent Perinephric Fat in Patients Undergoing Partial Nephrectomy

Launched by CENTRE OF POSTGRADUATE MEDICAL EDUCATION · May 31, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a condition called adherent perinephric fat (APF) in patients who are undergoing a type of kidney surgery known as partial nephrectomy. APF is a type of fat that sticks to the kidney, and while it's a common issue that doctors see, we still don’t fully understand how it affects surgery outcomes. The researchers want to find out more about what causes this fat to adhere and how it impacts the success of surgery and the patient's recovery. They will collect blood samples and medical information from participants, including details about their overall health and the characteristics of the kidney tumors. Participants will be followed for up to five years after their surgery to see how they do.

To be eligible for this study, participants must be at least 18 years old and scheduled for partial nephrectomy due to a specific type of kidney tumor. They should not have had prior kidney cancer or surgeries that could interfere with the study. Participants will need to give their consent to join the study and will have their health monitored before and after the surgery. This trial could help doctors better understand how APF affects kidney surgery, leading to improved treatment and better outcomes for patients with kidney tumors.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients qualified for partial nephrectomy by open, laparoscopic, or robotic method
• • Tumor stage cT1a-cT1b according to Tumour Node Metastasis classification
• • Age ≥ 18 years
• • Written consent to participate in the study
• Exclusion Criteria:
• • Patient does not give consent to participate in the study
• • Patients with recurrent kidney cancer, or who have undergone other surgeries within the kidney
• • Lack of preoperative imaging available for assessment
• • Missing medical documentation that prevents data analysis