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Search / Trial NCT05887440

Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust

Launched by RENNES UNIVERSITY HOSPITAL · May 24, 2023

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

Stroke Extensor Thrust Resistance Training Isokinetic Walking Speed Rehabilitation

ClinConnect Summary

This clinical trial is studying how a special type of exercise, called isokinetic strength training, can help people who have weakness on one side of their body (hemiparesis) walk better. This condition often occurs after a stroke, and patients may experience difficulty with their knee movement while walking. The goal of the study is to see if strengthening the knee muscles can improve walking performance in these patients, particularly those who have trouble with their knees extending properly while standing.

To be eligible for this study, participants must be between 18 and 75 years old, able to walk 10 meters independently without using any walking aids, and have experienced a stroke in the past six months to several years. Participants will need to sign consent forms and be part of a rehabilitation program that includes this strength training. If you or someone you know is interested in participating, please note that there are certain health conditions that would exclude someone from joining, such as severe heart problems or knee pain that could interfere with exercise. Overall, this trial is an opportunity for eligible individuals to potentially improve their walking ability through targeted strength training.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Hemiparetic patient (hemorragic or ischemic stroke)
  • Subacute stage (\< 6 Months) ou chronic stage of stroke (\> 6 months) (6 patients in each group)
  • Age between 18 and 75 years
  • Able to walk 10 meters independently without any assistive devices
  • Knee extension thrust during stance phase of gait cycle (rapid posterior movement of the knee toward extension)
  • Scheduled rehabilitation program with isokinetic strength training
  • affiliation to a social security
  • Patients who received and signed informed consent
  • Exclusion Criteria:
  • Major comprehension deficit that not allow to give informed consent and participate to isokinetic strength training (assessed with comprehension subscore of Langague screening Test)
  • non stable (unstable cardiovascular condition)
  • musculoskeletal disorders with knee pain that not allowed isokinetic strength training
  • Botulinum toxin injection less than 3 months or repeated injection in lower limb,
  • Proprioception trouble assessed with proprioception section of the Fugl-Meyer Assessment \[FMA-P\] 0/2
  • spasticity of triceps surae ≥2 (Modified Ashworth scale)
  • ankle dorsiflexion angle less than 90°
  • pregnant women or breastfeeding
  • persons with safety measure

About Rennes University Hospital

Rennes University Hospital, a leading academic medical center in France, is dedicated to advancing healthcare through innovative clinical research and trials. With a strong emphasis on patient-centered care, the hospital integrates cutting-edge scientific research with clinical practice, fostering collaboration among multidisciplinary teams. Its commitment to excellence is reflected in its robust infrastructure and expertise in various medical fields, enabling the development and evaluation of novel therapies and treatment protocols. By participating in clinical trials, Rennes University Hospital aims to enhance patient outcomes and contribute to the global body of medical knowledge.

Locations

Rennes, , France

Patients applied

0 patients applied

Trial Officials

Sophie HAMEAU, PhD

Principal Investigator

Rennes University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported