Evolution of Sexual Life Quality of Women With POI Before and After Introduction of Hormone Replacement Therapy

Launched by UNIVERSITY HOSPITAL, BORDEAUX · May 25, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how hormone replacement therapy (HRT) can improve the sexual quality of life for women who have been diagnosed with Premature Ovarian Failure (POI). POI occurs when a woman's ovaries stop functioning properly before the age of 40, leading to symptoms like missed periods and hormonal changes. The study will assess changes in sexual quality of life before and after starting HRT using a specific questionnaire.

To participate in this trial, women aged between 65 and 74, who have been diagnosed with POI and are not currently receiving hormone treatment, may be eligible. It's important that participants can understand the study and give their consent. However, women with certain health conditions, such as a history of hormone-related cancer or stroke, cannot join. Those who take part can expect to share their experiences and feelings about their sexual life before and after beginning the treatment, helping researchers understand the benefits of HRT for women with POI.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • positive diagnosis of POI (amenorrhea \> 4 months or spaniomenorrhea \> 4 months and FSH \> 25 IU/L checked twice, more than 4 weeks apart)
• • absence of hormonal treatment,
• • patient's oral consent,
• • affiliated or beneficiary of health insurance
• Exclusion Criteria:
• • contraindication to hormonal treatment (history of hormone-dependent cancer, history of ischemic arterial stroke),
• • inability of the patient to understand the nature or risks or significance and implications of the clinical investigation,
• • patient under legal protection