Ridge Preservation Using Different Techniques

Launched by TRI-SERVICE GENERAL HOSPITAL · May 26, 2023

Keywords

ClinConnect Summary

This study is exploring the best ways to preserve the jawbone after a tooth is removed, so the area can support future implants or dentures. It’s a randomized, double-masked trial, meaning participants and most people measuring the results don’t know which preservation method you receive. Researchers are comparing several techniques that use a bone graft with different coverings, such as palate-derived grafts, collagen membranes, or other special barrier membranes, against the option of spontaneous healing (no extra covering). Participants will be followed for up to a year with imaging and measurements to see how the soft tissue (gums) and hard tissue (bone) change at the extraction site.

People who may be eligible are adults aged 20 and older who need a tooth pulled and will need an implant or denture later. Eligible individuals should be generally healthy with good oral hygiene, have at least 2 mm of keratinized gum on both sides of the area, are not pregnant, and do not smoke heavily (less than or equal to 20 cigarettes a day). They also should not have uncontrolled diabetes or conditions or medications that impair wound healing. The trial is currently enrolling by invitation at Tri-Service General Hospital in Taipei, Taiwan, with about 130 participants planned and a completion date around March 2026. If eligible and enrolled, you would be randomly assigned to one of the preservation methods and have follow-ups at about 2 weeks, 4 weeks, 12 weeks, and 24 weeks, including imaging and a brief pain questionnaire at 14 days. Results are not yet available.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • \>20 years old
• • No contraindications for invasive dental procedures.
• • Not pregnant.
• • Teeth need to be extracted due to malocclusion or broken teeth.
• • Requires dental implant or denture fabrication after tooth extraction.
• • Healthy soft tissue (probing bleeding index \<20%, plaque index \<20%).
• • At least 2mm of keratinized gingiva on the buccal and lingual sides.
• • No need for simultaneous bone augmentation surgery during implant placement.
• • Willing to participate in and sign the consent form for this trial.
• Exclusion Criteria:
• • Poor oral hygiene maintenance.
• • Uncontrolled periodontal disease.
• • Heavy smoker (smokes \>20 cigarettes per day).
• • Uncontrolled diabetes.
• • Alcohol abuse.
• • Currently receiving medication treatment affecting wound healing (osteoporosis medication, radiation or chemotherapy).