Study on Brain Function of Obesity Classification

Launched by SHANGHAI 10TH PEOPLE'S HOSPITAL · May 27, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring how different types of obesity affect brain function. Researchers want to understand the similarities and differences in brain activity among four specific subtypes of obesity. They are also looking at how changes in brain function relate to health improvements and complications that can occur after weight loss. The study includes 120 participants with obesity and 30 healthy individuals with normal body weight.

To be eligible for this trial, participants should be between 16 and 65 years old and have a body mass index (BMI) over 37.5, or a BMI over 32.5 if they also have diabetes. However, individuals with certain medical conditions, such as hormonal disorders or severe heart and kidney issues, cannot participate. Those who join the study can expect to undergo assessments related to their brain function and how it connects to their weight and overall health. This research could help improve treatment options for obesity in the future, making it an important area of study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age ranged from 16-65 years old
• • BMI over 37.5kg/m2, or BMI over 32.5kg/m2 with diabetes which meets the recommended cut-off bariatric surgery of the Guidelines for surgical treatment of obesity accompanied with or without type 2 diabetes in China.
• Exclusion Criteria:
• • secondary causes of obesity such as hypothalamic obesity, Cushing syndrome, hypophysis dysfunction, etc
• • pregnancy or location
• • contraindications for laparoscopic surgery, such as gastrointestinal diseases of intra-abdominal infection, adhesion, etc
• • severe heart, liver, and kidney dysfunction
• • organic and systemic diseases intolerant of surgery.