Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy

Launched by BETH ISRAEL DEACONESS MEDICAL CENTER · May 31, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at whether using nitrous oxide, a type of gas commonly known as laughing gas, can help reduce pain and anxiety during a vasectomy, which is a surgical procedure for men. The unique part of this study is that patients will have the ability to control how much nitrous oxide they receive during the procedure, which might lead to a better overall experience and higher satisfaction.

To join the study, participants need to be men aged between 21 and 85 who are scheduled for a vasectomy and can safely use nitrous oxide. They should also have access to email and a computer to complete surveys. However, a few individuals won’t be eligible, including those with certain medical conditions or those who have had recent surgeries. If you choose to participate, you can expect to receive nitrous oxide during your vasectomy and be able to adjust how much you inhale, potentially making the procedure more comfortable for you.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Scheduled for vasectomy
• • 2. Aged 21 to 85 years
• • 3. Suitable for receipt of inhaled nitrous oxide/oxygen
• • 4. Access to an email and computer
• Exclusion Criteria:
• • 1. Perioral facial hair impeding good mask seal
• • 2. Cognitive impairment that impedes ability to complete survey questions
• • 3. Intent to use benzodiazepines or opioids "as needed" for purposes of vasectomy
• 4. Has any of the following medical conditions, which contraindicate use of nitrous oxide:
• • 1. Inner ear, bariatric or eye surgery within the last 2 weeks,
• • 2. Current emphysematous blebs,
• • 3. Severe B-12 deficiency,
• • 4. Bleomycin chemotherapy within the past year,
• • 5. Heart attack within the past year,
• • 6. Stroke within the past year,
• • 7. Class III or higher heart failure.