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Search / Trial NCT05897086

Polyethylene-glycol Assisted Nerve Repair in Phalloplasty

Launched by VANDERBILT UNIVERSITY MEDICAL CENTER · Jun 1, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Phalloplasty

ClinConnect Summary

With more than 1.6 million transgender and nonbinary (TGNB) individuals in the United States, the investigators have witnessed an exponential increase in the number of gender-affirming surgeries performed in the last 2 decades. Of the affirming surgical spectrum, "bottom" genitourinary surgeries remain the most challenging. Specifically, phalloplasty is a masculinizing surgery for neophallus creation using free tissue transfer from other parts of the body and microvascular techniques for nerve and vessel reattachment. In radial forearm free flap (RFFF) phalloplasty, nerves from the forearm ...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • over the age of 18
  • preoperative diagnosis of gender dysphoria and present for planned radial forearm free flap phalloplasty
  • willing to comply with all aspects of treatment as well as the study evaluation schedule
  • Exclusion Criteria:
  • a known allergy to the study drug
  • a hematocrit of 54% or higher
  • a history of venous thromboembolism (VTE), peripheral phlebitis, stroke, or myocardial infarction within the last 6 months.

About Vanderbilt University Medical Center

Vanderbilt University Medical Center (VUMC) is a leading academic medical center located in Nashville, Tennessee, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, VUMC integrates cutting-edge scientific inquiry with patient-centered care, supporting a diverse array of studies aimed at enhancing medical knowledge and improving treatment outcomes. With a robust infrastructure and a multidisciplinary team of experts, VUMC fosters collaboration across various fields, ensuring the highest standards of safety and ethical considerations in its research endeavors. Through its dedication to medical discovery and education, VUMC plays a pivotal role in shaping the future of medicine.

Locations

Nashville, Tennessee, United States

Nashville, Tennessee, United States

Patients applied

0 patients applied

Trial Officials

Wesley Thayer, MD

Principal Investigator

Vanderbilt University Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported