Anesthesia Induction Schemes of Electroconvulsive Convulsions in Patients With Depression Based on EEG Monitoring

Launched by MIN SU · Jun 9, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how different methods of giving anesthesia can affect the quality of electroconvulsive therapy (ECT) for patients with moderate to severe depression. ECT is a treatment that uses small electric currents to help improve symptoms of depression, especially in cases where other treatments haven't worked well. The researchers want to find the best way to use anesthesia so that patients have effective seizures during the procedure while also minimizing any negative side effects on their thinking and memory.

To participate in this trial, you need to be between 18 and 60 years old and diagnosed with moderate to severe depression. You should not have certain health conditions, such as bipolar disorder or severe physical illnesses, and you must be able to understand the study and provide consent. If you join the trial, you can expect to receive either a standard or modified anesthesia approach, and the researchers will closely monitor your brain activity to see which method works best. This study aims to improve ECT outcomes while keeping patients comfortable and safe.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • In-patients who meet the diagnostic criteria of moderate and severe depression in the 11th edition of the International Classification of Diseases (ICD-11)
• • Age 18-60 years old, gender unlimited
• • Primary school or above education level
• • Indications for MECT treatment
• • Normal hearing and vision (including color discrimination)
• • The patient voluntarily participated in the study and signed the informed consent form, and the guardian also signed the informed consent form.
• Exclusion Criteria:
• • History of physical disease, brain organic disease and abuse of alcohol and psychoactive substances
• • Patients with bipolar disorder
• • Primary insomnia
• • Combined with other mental diseases
• • Combined with obesity, diabetes and other metabolic diseases
• • Combined with hypertension, cardiovascular disease or cerebrovascular disease
• • Combined with Alzheimer's disease
• • Pregnant and lactating women.