Effect of Iodine-containing Multiple Micronutrient During Lactation on Infant Neurodevelopment

Launched by BROWN UNIVERSITY · Jun 5, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how taking iodine-containing multiple micronutrient supplements affects the development of infants whose mothers are breastfeeding in areas where iodine levels are low. The researchers want to find out if these supplements help improve infant brain development, the level of iodine in breast milk, and the health of both mother and baby’s thyroid, which is an important gland that helps control metabolism and growth.

To participate, mothers need to plan to breastfeed for at least three months and have a healthy baby weighing more than 2000 grams at birth. Those who primarily plan to use formula or have certain health conditions, like HIV or severe developmental disorders in their infants, are not eligible. If selected, mothers will take a daily supplement for six months and provide some samples of breast milk and blood, while infants will also provide blood and urine samples. Researchers will compare the outcomes of mothers taking the supplements with those receiving regular postnatal care to see if there are any benefits to infant development and health.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Intention to breast feed at least 3 months
• • Birth weight \>2000g
• Exclusion Criteria:
• • Intention to primarily feed by alternative sources (formula, animal milk)
• • Multiple pregnancy
• • Infant with major congenital anomalies
• • Infants with severe morbidity or developmental disorder
• • Mother with HIV or chronic renal disease
• • Plan to move out of study catchment area
• • Does not agree to follow up or EEG/VEP