Diaphragmatic Function as a Biomarker

Launched by RWTH AACHEN UNIVERSITY · Jun 5, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how well the diaphragm, the main muscle used for breathing, works in people with respiratory diseases like asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and pulmonary hypertension. The researchers want to understand if problems with diaphragm function could explain why some patients experience shortness of breath, a common symptom in these conditions. By studying this, they hope to find a new way to assess and possibly predict how well patients with these lung diseases might do over time.

To participate in the trial, you need to be at least 18 years old and diagnosed with one of the lung diseases mentioned. You should also be able to understand the study and follow instructions. However, there are some reasons you might not be able to join, such as having a very high body mass index (BMI) or certain medical conditions. If you decide to participate, you can expect to undergo evaluations related to your diaphragm function, and your involvement could help improve understanding of breathing difficulties in lung disease patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patient has one of the following lung diseases: COPD, bronchial asthma, pulmonary fibrosis, pulmonary hypertension
• • is 18 years or older
• • is mentally and physically able to understand the study and to follow instructions
• • are legally competent
• • signed declaration of consent
• Exclusion Criteria:
• • BMI \> 35
• • current or treatments or diseases in the past which could influence the evaluation of the study
• • Expected lack of willingness to actively participate in study-related measures
• • alcohol or drug abuse
• • disc herniation/prolapse
• • epilepsy
• • wheelchair bound
• • in custody due to an official or court order
• • in a dependent relationship or employment relationship with investigating physician or one of their deputy
• • emergency inpatient hospital stay within 4 weeks before study-specific examinations