Ultra-Low Contrast Angiography in AKI

Launched by TULANE UNIVERSITY · Jun 7, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new method called ultra-low contrast coronary angiography, which is a type of imaging test used to look at the blood vessels of the heart. The goal is to see if this method is safe for patients who already have acute kidney injury (AKI), a condition where the kidneys suddenly stop working properly.

To participate, patients must be hospitalized and either have AKI when they are admitted or develop it during their stay. However, there are some important criteria that might prevent someone from joining, such as having stable kidney function or needing urgent heart procedures that can't wait. If eligible, participants can expect to undergo the angiography procedure with ultra-low contrast, which aims to reduce potential harm to their kidneys. This trial is not yet recruiting, so it will be important to keep an eye on when it begins.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Hospitalized patients who have AKI at admission or who develop AKI during admission and require invasive coronary angiography will be included in the trial.
• Exclusion Criteria:
• • Stabilized renal function manifested by unchanged or downtrending serum creatinine during a 24-hour period prior to enrollment.
• • Contraindication for invasive coronary angiography other than AKI.
• • Percutaneous coronary intervention is indicated and cannot be postponed by 7 days.
• • Need for renal replacement therapy before coronary angiography or planned renal replacement therapy after coronary angiography (if premeditated before coronary angiography).
• • Administration of intravascular contrast media during 7 days prior to the coronary angiography or within 6 days after coronary angiography.
• • Pregnant patients, prisoners, cognitively impaired subjects, age below 18 years, unable or unwilling to provide informed consent.