Non-invasive Ultrasound Retinal Stimulation for Vision Restoration
Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Jun 19, 2023
Trial Information
Current as of July 25, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is exploring a new way to help people with vision loss due to age-related macular degeneration (AMD) and retinitis pigmentosa (RP). Researchers are testing a non-invasive device that uses high-frequency ultrasound to stimulate the retinal nerve cells in the eye, which could potentially restore some vision. Unlike other methods that require surgery and can be risky, this ultrasound approach is designed to be safer and easier for patients. The study will follow strict safety guidelines to protect everyone involved.
To participate, individuals need to be 18 years or older and have a diagnosis of AMD or RP without any other serious eye conditions. Participants will undergo some eye scans before and after using the ultrasound device and will experience several cycles of stimulation. They will also fill out a questionnaire to share their experiences and any changes in their vision during the process. It's important to note that this study is not yet recruiting participants, but it aims to find safe ways to help those with specific vision problems regain some sight.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Diagnosis of AMD (regardless of stage and type) or RP. At least two volunteers should diagnose with RP.
- • 2. Age 18 years or older
- • 3. No other eye-related health conditions
- • 4. No allergic history to commercial ultrasound gel
- • 5. Must be willing and able to comply with the protocol testing
- Exclusion Criteria:
- • 1. Declining to participate and inability to give informed consent.
- • 2. Unable to comply with the process of the research
- • 3. If the volunteer has optic nerve disease, including the history of glaucoma, optic neuropathy, or other confirmed damage to optic nerve or visual cortex damage
- • 4. Unable to fixate that hinders obtaining high-quality imaging
- • 5. High myopia; refractive error of six diopters and above
- • 6. Pregnancy
- • 7. Subject is participating in another investigational drug or device study that may conflict with the objectives, follow-up, or testing of this study
About University Of Southern California
The University of Southern California (USC) is a prestigious research institution located in Los Angeles, California, known for its commitment to advancing knowledge and innovation in various fields, including medicine and health sciences. As a clinical trial sponsor, USC leverages its extensive resources, interdisciplinary expertise, and state-of-the-art facilities to conduct cutting-edge research aimed at improving patient outcomes and public health. The university fosters collaboration among its diverse faculty and students, ensuring a dynamic environment for the development and implementation of clinical studies that adhere to the highest ethical and scientific standards. Through its clinical trials, USC aims to contribute to the advancement of medical science and the translation of research findings into practical applications that benefit communities locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Qifa Zhou, PhD
Principal Investigator
University of Southern California
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported